As a result of this project, we will have a better understanding of who speaks for the government during an outbreak, the kind of information they share, and how their messages are understood by the public. Besides the speed, this approach has the merit to induce a broad CTL immune response that should also trigger protection to any strains of the virus that are related to the Wuhan virus, like the SARS virus of 2002. The research team will 1)Carry out rapid genomic sequencing on patient samples to study the virus, how it spreads, how it evolves and predict which drugs will work 2)Develop knowledge of how the virus characteristics, along with a patient's previous health conditions, impact the severity of illness and how they recover from the illness 3)Develop a software tool (PLOVER 2.0) that will allow us to carry out this research and will also make the data viewable by key stakeholders such as Medical Health Officers. A rapid digital landscape analysis will also be done as a part of this research. There are many unanswered questions regarding the virus, how it spreads and the disease that it causes. We have assembled a team consisting of biochemists, chemists, virologists, engineers, and clinicians offering deep skills in four highly significant fields to help address this rapidly evolving SARS-CoV_2 crisis. To continue to contribute to global efforts to address the COVID-19 outbreak, the Government of Canada is investing an additional $25.8M in research. This will prevent the spread of COVID-19 and its potential negative consequences. Combating misinformation, fear and stigma in response to the Covid-19 outbreak: An international collaboration between Canada and Singapore.

We will search for potential drugs that bind to the 2019-nCoV pseudoknot and disrupt PRF. The observational study will build on work that we have been doing for the past four years, with pre-established protocols and data collection infrastructure just for this purpose. A novel zoonotic coronavirus (SARS-CoV-2) has recently been identified in patients with an acute and potentially fatal respiratory disease (COVID-19). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 produces a key enzyme, nsp12, essential for replicating the viral genome. In addition to testing the effectiveness of our specific intervention, the master protocols and procedures developed can be used to test other prevention interventions including both medications and vaccines, once they become available. We will meet the call's objectives of contributing to the global response to the COVID-19 outbreak, strengthening the understanding of its public impacts, and providing evidence to inform public health planning, decision making and response. Georgian will receive a $33,476 grant, the first CFI grant for the college. If this study is successful, ARBs can potentially limit complications and mortality of COVID-19. As a result of the rapid transmission internationally, a global call to control the spread of the virus in affected and non-affected areas has been implemented.

This will be achieved through coordinated efforts across communities, professionals, and local residents, to address three specific and inter-related objectives: 1) assessing GTA Chinese immigrants' knowledge, attitudes/beliefs, and protection practices toward COVID-19; 2) developing, evaluating, and optimizing a mutual-support quarantine network to contain COVID-19 from further spreading; and 3) assessing the psychological impacts and the associated predictors of the potential COVID-19 outbreak. Cependant, lorsqu'une personne est soumise a une menace reelle et imminente, elle ressent du stress et de la peur. This research program targets a key mechanism of COVID-19 transmission, that is, transport of the virus through heating, ventilation, and air conditioning (HVAC) systems with subsequent inhalation by other people. In particular we examine how characteristics of the organizational response to disease outbreaks influence employees' own health and health-promoting behaviours.

However, despite the high sensitivity of these methods, they are not suitable for rapid and large-scale screening for multiple samples because of their long analysis time. The 2019-novel coronavirus (SARS CoV-2) is a major sanitary and economical threat to all countries. In a few weeks, the number of confirmed cases of COVID-19 infection has dramatically increased.

This proposal will develop tools that can be shared with the world scientific community that will help further our understanding of viral pathogenesis, transmission as well as screen potential small-molecule inhibitors and antibodies. We will be writing reports and papers that help Alberta and other provinces plan for future public health emergencies. Actuellement, nous ne connaissons pas la reaction des professionnels de la sante lorsqu'ils font face a une menace imminente tel que le SARS-CoV-2.

Our team will combine its multidisciplinary expertise to develop genetically engineered antibodies that can be used as therapeutics to limit the spread of the virus, as well as help identify the virus in patient samples. Assessing and Mitigating the Food Security Consequences of COVID-19 in China.

Deuxiemement, une serie de six etudes experimentales sera menee afin de tester l'efficacite des divers messages sur le coronavirus tels que transmis par les agents publics et par les divers medias sociaux tels que Facebook. Moreover, these methods need skilled personal to perform and not suitable for point-of-care testing. In this work we will develop therapeutics based on human antibodies that can be used in the treatment of COVID-19. The Greater Toronto Area (GTA) has one of the largest Chinese communities in the world and thus bears the brunt of the fear, anxiety, and panic.

As public health authorities increase efforts to address the new coronavirus epidemic (COVID-19), rumours, misinformation, and xenophobic online posts are spreading faster than the virus. "; "when will it end? Second, we will design and prepare a second vaccine component that will elicit the production of neutralizing antibodies to the SARS-CoV-2. In addition, AptaGO-based a low-cost (<$1 per test) platform while being ultrasensitive (protein equivalent of <100 virions), thus making them ideal for the proposed use. Countermeasures to the supply chain disruptions in medical and pharmaceutical industries. We propose conducting research into COVID-19 misinformation from multiple angles, developing effective communication and education tools, countering misinformation strategically, and providing policy recommendations to deal with COVID-19 and future outbreaks. Coronaviruses are associated with a variety of human diseases ranging from the common cold to new and serious conditions such as Severe Acute Respiratory Syndrome (SARS), which emerged in 2002, Middle Eastern Respiratory Syndrome (MERS), first reported in 2012, and a recent and still growing outbreak of COVID-19, caused by the coronavirus SARS-CoV-2. The public health sector can use social media during emergency events for: 1) public health messaging, 2) monitoring misinformation, and 3) responding to questions and concerns raised by the public.

The project is a collaboration between Georgian College and 360 Technology and Innovation Group Inc. Read more: A detailed 3D structure of the SARS-CoV-2 3CLpro enzyme was recently solved, and this provides enough information to identify chemical structures of molecules that are likely to block its action, through a procedure known as virtual screening. This investment will support 49 researchers across the country whose teams will focus on developing and implementing measures to rapidly detect, manage, and reduce the transmission of COVID-19.

The impact of this course of research will be significant, enabling the development of strategies to combat misinformation, stigma, and fear, to address their underlying drivers, and to improve public awareness, knowledge, and trust. Production of a recombinant S ( spike ) protein vaccine against SARS-CoV-2 and emerging coronaviruses. Nov 6, 2020 2:14 PM. Quarantine, limitations in movement and public gathering, and other restrictive measures can put a social and economic burden on individuals, which may be disproportionate, depending on their socioeconomic status and other factors. Outbreaks such as the novel coronavirus (COVID-19) can result in inappropriate, excessive and counterproductive measures that hinder global coordination of outbreak response.

Although development of vaccines and drugs targeting the virus are ramping up, none of these addresses host response of COVID-19 infections directly. You will not receive a reply. This research program will include: 1) a thorough review of building science literature related to airborne virus transmission; 2) a policy directive for governing organizations who inform owners and operators of ventilation systems and building code bodies; 3) an inventory and assessment of over 100 buildings with diverse ventilation systems; and 4) an inventory and assessment procedure and protocol for other buildings. In more severe cases, the infection can cause respiratory failure, severe acute respiratory syndrome, kidney failure, and death. Next, we will conduct a representative survey of all Canadians which will assess their knowledge levels about SARS-CoV-2 including the prevalence, lethality, modes of infection and perceived personal risk of acquiring the virus. An epidemic caused by a novel coronavirus (SARS-CoV-2) has spread rapidly in China and 27 other countries. Two urgent questions need to be addressed. The outbreak of a respiratory illness (COVID-19) in China at the end of December 2019 has been demonstrated to be caused by a new coronavirus. We have successfully validated these tools for COVID-19 forecasting during the course of this epidemic and published our results in peer-reviewed literature. The coronavirus (COVID-19) has triggered fear worldwide, and in Canada, some of this fear has been misplaced onto Chinese Canadians. These routines also pose extra work in a system where nurses are already working to capacity.

This project will for the first time (1) analyze and describe the ethical pathways for R&D that existed or were established for EVD in order to aid the global research community in navigating these pathways for COVID-19 R&D; (2) analyze and describe the ethical pathways as they are established and navigated for COVID-19 R&D in order to rapidly support ongoing and future COVID-19 R&D; and (3) compare and conduct an ethical analysis of the ethical pathways for EVD and COVID-19 R&D to inform future R&D during epidemics.



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